An Esquire is in essence a Telecaster with no neck pickup. It was wired with three setting: a bassy setting to cover the the low-end (not really a common position), a standard volume-and-tone setting, and one where you bypass the tone knob and go right to the jack. This is a bit of a hot-rod wiring.
My suggestion was to get a Squier Classic Vibe '50s Tele and mod it, because TDPRI is all over these things as being very good early Tele repros for not much money, so you can get solid standard hardware and change what you want.
I'm not really in the market for that, but I'm always curious, so I started searching and saw this:
Sweetwater created the FENDER® Sweet-Mod Classic Vibe '50s Telecaster® to give you a hot-rodded Fender experience right out of the case. We start with the tried-and-true Fender Classic Vibe '50s Telecaster®, supercharged with DiMarzio Area T stacked humbucking pickups for big, fat, aggressive tone. You get the iconic look and feel of the Classic Vibe '50s Telecaster, with a seriously upgraded sound courtesy of Sweetwater's factory-authorized guitar workshop. You were probably going to do these modifications anyway, and our expert guitar techs have already done the work - for less than your local guitar tech would likely charge. No other retailer has the Fender Sweet-Mod Classic Vibe '50s Telecaster, and it's made to pack an amazing sonic punch.
"You were probably going to do it anyway."
There's a number of different choices. Teles get either Fender Noiseless or DiMarzio Area Ts. (Stratoblogster can tell you the Strat options. That's his job!) No Esquire options (because you'd have to swap out the pickguard, too, I think). I must say, I'm wanting.